Correct!

1. Viral bronchitis

Both the physical examination and chest x-ray are normal. This makes pneumonia and congestive heart failure unlikely. There is no history of COPD which would be unlikely with a 20 pack-year history of smoking. Drug reaction is possible with amiodarone being the most likely cause but is much less common than a respiratory tract infection.

She was asked to return for follow up a week later. She returns with worsening symptoms and was admitted to the hospital.

Laboratory evaluation shows a slightly low hemoglobin 11.6 g/dL and an elevated white blood cell count of 11,100 cells/μL and an elevated neutrophil count (90% neutrophils).

Repeat chest x-ray is show in figure 2.

Figure 2. Repeat chest x-ray on week after the x-ray show in figure 1 showing the PA (Panel A) and lateral (Panel B) views.

A CT scan was performed (Figure 3).

Figure 3. Representative images from the thoracic CT scan.

The patient was started on piperacillin-tazobactam, levofloxacin, and doxycycline. Worsening of cough and pleuritic chest pain were noted. Sputum cultures and smears were negative.

Which of the following is the next step in her evaluation?

  1. PET scan
  2. CT angiography
  3. Bronchoscopy with bronchoalveolar lavage (BAL)
  4. Needle biopsy
  5. Video-assisted thorascopic (VATS) biopsy

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